Apr 12, 2016. As the idio-binding receptor of IgG Fc, it plays an important role in the antibody-dependent cellular cytotoxicity of natural killer cells. As part of the mono-nuclear phagocytic system, Kupffer cells (KCs) are the main type of hepatic macrophages, and they play an important role in the inhibition of liver tumors.
FcγRIIIa (CD16) is a low-affinity Fc receptor of IgG. Download Free Hacking Safeguard Easy Encryption. As the idio-binding receptor of IgG Fc, it plays an important role in the antibody-dependent cellular cytotoxicity of natural killer cells. The aim of the present study was to investigate the distribution of Kupffer cells (KCs) and the expression of their surface receptor FcγRIIIa in hepatocellular carcinoma. Furthermore, we also aimed to observe the functional mechanism of FcγRIIIa. Immunohistochemical analysis was employed to study KCs and FcγRIIIa.